Needle-type organic electrochemical transistor for spatially resolved detection of dopamine

In this work, the advantages of carbon nanoelectrodes (CNEs) and orgonic electrochemical transistors (OECTs) were merged to realise nanometre-sized, spearhead OECTs based on single- and double-barrel CNEs functionalised with a conducting polymer film. The needle-type OECT shows a high aspect ratio that allows its precise positioning by means of a macroscopic handle and its size is compatible with single-cell analysis. The device was characterised with respect to its electrolyte-gated behaviour and was employed as electrochemical sensor for the proof-of-concept detection of dopamine (DA) over a wide concentration range (\(10^{−12}—10^{−6}\) M). Upon application of fixed drain and gate voltages (\(V_{d} = − 0.3 V, V_{g}\) = − 0.9 V, respectively), the nano-sized needle-type OECT sensor exhibited a linear response in the low pM range and from 0.002 to 7 \(\mu\)M DA, with a detection limit of 1 × \(10^{−12}\) M.

Metadaten
Author:	Federica Mariani ORCiD GND, Thomas Quast ORCiD GND, Corina Andronescu ORCiD GND, Isacco Gualandi ORCiD GND, Beatrice Fraboni ORCiD GND, Domenica Tonelli ORCiD GND, Erika Scavetta ORCiD GND, Wolfgang Schuhmann ORCiD GND
URN:	urn:nbn:de:hbz:294-92925
DOI:	https://doi.org/10.1007/s00604-020-04352-1
Parent Title (English):	Microchimica Acta
Publisher:	Springer
Place of publication:	Wien
Document Type:	Article
Language:	English
Date of Publication (online):	2022/09/20
Date of first Publication:	2020/06/09
Publishing Institution:	Ruhr-Universität Bochum, Universitätsbibliothek
Tag:	Bioelectronics; Dopamine; Nanoelectrode; Organic electrochemical transistor; PEDOT:PSS
Volume:	187
Issue:	Artikel 378
First Page:	378-1
Last Page:	378-11
Note:	Dieser Beitrag ist auf Grund des DEAL-Springer-Vertrages frei zugänglich.
Institutes/Facilities:	Lehrstuhl für Analytische Chemie - Elektroanalytik & Sensorik
	Lehrstuhl für Analytische Chemie
Dewey Decimal Classification:	Naturwissenschaften und Mathematik / Chemie, Kristallographie, Mineralogie
open_access (DINI-Set):	open_access
faculties:	Fakultät für Chemie und Biochemie
Licence (English):	Creative Commons - CC BY 4.0 - Attribution 4.0 International

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