Mehdi Behroozi, Xavier Helluy, Felix Ströckens, Meng Gao, Roland Pusch, Sepideh Tabrik, Martin Tegenthoff, Tobias Otto, Nikolai Axmacher, Robert Kumsta, Dirk Moser, Erhan Genç, Onur Güntürkün
- Animal-fMRI is a powerful method to understand neural mechanisms of cognition, but it remains a major challenge to scan actively participating small animals under low-stress conditions. Here, we present an event-related functional MRI platform in awake pigeons using single-shot RARE fMRI to investigate the neural fundaments for visually-guided decision making. We established a head-fixated Go/NoGo paradigm, which the animals quickly learned under low-stress conditions. The animals were motivated by water reward and behavior was assessed by logging mandibulations during the fMRI experiment with close to zero motion artifacts over hundreds of repeats. To achieve optimal results, we characterized the species-specific hemodynamic response function. As a proof-of-principle, we run a color discrimination task and discovered differential neural networks for Go-, NoGo-, and response execution-phases. Our findings open the door to visualize the neural fundaments of perceptual and cognitive functions in birds—a vertebrate class of which some clades are cognitively on par with primates.
MetadatenAuthor: | Mehdi BehrooziORCiDGND, Xavier HelluyGND, Felix StröckensORCiDGND, Meng GaoGND, Roland PuschORCiDGND, Sepideh TabrikGND, Martin TegenthoffGND, Tobias OttoORCiDGND, Nikolai AxmacherORCiDGND, Robert KumstaORCiDGND, Dirk MoserORCiDGND, Erhan GençGND, Onur GüntürkünORCiDGND |
---|
URN: | urn:nbn:de:hbz:294-94337 |
---|
DOI: | https://doi.org/10.1038/s41467-020-18437-1 |
---|
Parent Title (English): | Nature communications |
---|
Publisher: | Springer, Nature Publishing Group UK |
---|
Place of publication: | London |
---|
Document Type: | Article |
---|
Language: | English |
---|
Date of Publication (online): | 2022/11/17 |
---|
Date of first Publication: | 2020/09/18 |
---|
Publishing Institution: | Ruhr-Universität Bochum, Universitätsbibliothek |
---|
Volume: | 11 |
---|
Issue: | Article 4715 |
---|
First Page: | 4715-1 |
---|
Last Page: | 4715-12 |
---|
Note: | Dieser Beitrag ist auf Grund des DEAL-Springer-Vertrages frei zugänglich. |
---|
Institutes/Facilities: | Institut für Kognitive Neurowissenschaft, Abteilung Biopsychologie |
---|
| Institut für kognitive Neurowissenschaften |
---|
Dewey Decimal Classification: | Philosophie und Psychologie / Psychologie |
---|
open_access (DINI-Set): | open_access |
---|
faculties: | Fakultät für Psychologie |
---|
Licence (English): | Creative Commons - CC BY 4.0 - Attribution 4.0 International |
---|