Mechanisms and efficacy of immunomodulatory therapies
- Efficacy of neuroprotective and immunomodulatory therapies in animal models of Huntingtons disease and multiple sclerosis were studied in this thesis. Beside behavioural tests, immunological, molecular biological, and histological analysis were performed to identify potential new mechanisms of action.
- In dieser Arbeit wurde die Effektivität neuroprotektiver und immunomodulatorischer Therapien in Tiermodellen der Huntington Erkrankung und der Multiplen Sklerose untersucht. Neben Verhaltenstests, wurden immunologische, molekularbiologische und histologische Analysen durchgeführt, um potentielle neue Wirkmechanismen zu identifizieren.
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| Author: | Christiane ReickORCiDGND |
|---|---|
| URN: | urn:nbn:de:hbz:294-41577 |
| Subtitle (English): | neuroprotective effects in chronic inflammatory and degenerative diseases of the central nervous system |
| Referee: | Ralf GoldORCiDGND, Stefan WieseORCiDGND |
| Document Type: | Doctoral Thesis |
| Language: | English |
| Date of Publication (online): | 2014/08/22 |
| Date of first Publication: | 2014/08/22 |
| Publishing Institution: | Ruhr-Universität Bochum, Universitätsbibliothek |
| Granting Institution: | Ruhr-Universität Bochum, International Graduate School of Neuroscience |
| Date of final exam: | 2013/06/20 |
| Creating Corporation: | International Graduate School of Neuroscience |
| GND-Keyword: | Nervendegeneration; Therapie; Immunmodulator; Huntington-Chorea; Neuroinformatik |
| Institutes/Facilities: | St. Josef-Hospital Bochum, Neurologische Klinik |
| Dewey Decimal Classification: | Naturwissenschaften und Mathematik / Biowissenschaften, Biologie, Biochemie |
| faculties: | International Graduate School of Neuroscience (IGSN) |
| Licence (German): |  Keine Creative Commons Lizenz - es gelten der Veröffentlichungsvertrag und das deutsche Urheberrecht |
