Impact of topical corticosteroids and early life risk factors on the incidence of pathologic bacteria in the lower respiratory tract

190 children consecutively undergoing bronchoscopy with bacterial cultures of bronchoalveolar lavage fluid (BALF) or bronchial aspirates (BA) from January 1999 until June 2001 were included in the study. 84 children were on topical corticosteroids (TCS) therapy and 106 children were not. The incidences of detected significant amounts of pathologic bacteria from BALF and BA were not significantly different between children on TCS (16.67%) and children without TCS (18.87%). Haemophilus influenzae, streptococcus pneumoniae and moraxella catarrhalis were the most common pathogens isolated from the BALF and BA in both groups of children with and without TCS. TCS, previous systemic steroid therapy, passive smoke exposure, antibiotic pre-treatment and premature birth neither had any influence on the incidence of bacterial pathogens in the lower respiratory tract nor on the types of bacteria involved.

Metadaten
Author:	Son Bui Binh Bao GND
URN:	urn:nbn:de:hbz:294-4533
Referee:	Christian Rieger GND, Baptist Gallwitz GND
Document Type:	Doctoral Thesis
Language:	English
Date of Publication (online):	2003/03/18
Date of first Publication:	2003/03/18
Publishing Institution:	Ruhr-Universität Bochum, Universitätsbibliothek
Granting Institution:	Ruhr-Universität Bochum, Medizinische Fakultät
Date of final exam:	2002/02/07
Creating Corporation:	Medizinische Fakultät
GND-Keyword:	Corticosteroide; Bakterien; Broncho-alveoläre Lavage, Bronchus / Sekret; Kind (0 - 14 Jahre)
Institutes/Facilities:	St. Josef-Hospital Bochum, Klinik für Kinder- und Jugendmedizin
Dewey Decimal Classification:	Technik, Medizin, angewandte Wissenschaften / Medizin, Gesundheit
faculties:	Medizinische Fakultät
Licence (German):	Keine Creative Commons Lizenz - es gelten der Veröffentlichungsvertrag und das deutsche Urheberrecht

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