Expression pattern of \(\it Axin2\) during chicken development

  • Canonical \(\it Wnt\)-signalling is well understood and has been extensively described in many developmental processes. The regulation of this signaling pathway is of outstanding relevance for proper development of the vertebrate and invertebrate embryo. \(\it Axin2\) provides a negative-feedback-loop in the canonical \(\it Wnt\)-pathway, being a target gene and a negative regulator. Here we provide a detailed analysis of the expression pattern in the development of the chicken embryo. By performing \(\textit {in-situ}\) hybridization on chicken embryos from stage HH 04+ to HH 32 we detected a temporally and spatially restricted dynamic expression of \(\it Axin2\). In particular, data about the expression of \(\it Axin2\) mRNA in early embryogenesis, somites, neural tube, limbs, kidney and eyes was obtained.

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Metadaten
Author:Gesa EckeiGND, Marion BöingGND, Beate Brand-SaberiORCiDGND, Gabriela Morosan-PuopoloORCiDGND
URN:urn:nbn:de:hbz:294-58511
DOI:https://doi.org/10.1371/journal.pone.0163610
Parent Title (English):PLoS one
Document Type:Article
Language:English
Date of Publication (online):2018/07/05
Date of first Publication:2016/09/28
Publishing Institution:Ruhr-Universität Bochum, Universitätsbibliothek
Tag:Open Access Fonds
Volume:11
Issue:9
First Page:e0163610-1
Last Page:e0163610-24
Note:
Article Processing Charge funded by the Open Access Publication Fund of Ruhr-Universität Bochum.
Note:
PLoS ONE, Bd. 11.2016, H. 9, Artikelnummer e0163610
Institutes/Facilities:Institut für Anatomie, Abteilung für Anatomie und Molekulare Embryologie
Dewey Decimal Classification:Naturwissenschaften und Mathematik / Biowissenschaften, Biologie, Biochemie
open_access (DINI-Set):open_access
faculties:Medizinische Fakultät
Licence (English):License LogoCreative Commons - CC BY 4.0 - Attribution 4.0 International