Anti-infective properties of the golden spice curcumin

  • The search for novel anti-infectives is one of the most important challenges in natural product research, as diseases caused by bacteria, viruses, and fungi are influencing the human society all over the world. Natural compounds are a continuing source of novel anti-infectives. Accordingly, curcumin, has been used for centuries in Asian traditional medicine to treat various disorders. Numerous studies have shown that curcumin possesses a wide spectrum of biological and pharmacological properties, acting, for example, as anti-inflammatory, anti-angiogenic and anti-neoplastic, while no toxicity is associated with the compound. Recently, curcumin’s antiviral and antibacterial activity was investigated, and it was shown to act against various important human pathogens like the influenza virus, hepatitis C virus, HIV and strains of \(\it Staphylococcus\), \(\it Streptococcus\), and \(\it Pseudomonas\). Despite the potency, curcumin has not yet been approved as a therapeutic antiviral agent. This review summarizes the current knowledge and future perspectives of the antiviral, antibacterial, and antifungal effects of curcumin.

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Metadaten
Author:Dimas PradityaORCiDGND, Lisa KirchhoffORCiDGND, Janina BrüningGND, Heni RachmawatiGND, Jörg Helmut SteinmannGND, Eike SteinmannORCiDGND
URN:urn:nbn:de:hbz:294-71316
DOI:https://doi.org/10.3389/fmicb.2019.00912
Parent Title (English):Frontiers in microbiology
Document Type:Article
Language:English
Date of Publication (online):2020/04/29
Date of first Publication:2019/05/03
Publishing Institution:Ruhr-Universität Bochum, Universitätsbibliothek
Tag:Open Access Fonds
anti-infective properties; bacteria; curcumin; fungi; natural products; nutraceutical; virus
Volume:10
Issue:Artikel 912
First Page:912-1
Last Page:912-16
Note:
Article Processing Charge funded by the Deutsche Forschungsgemeinschaft (DFG) and the Open Access Publication Fund of Ruhr-Universität Bochum.
Institutes/Facilities:Institut für Hygiene und Mikrobiologie, Abteilung für Molekulare und Medizinische Virologie
Dewey Decimal Classification:Naturwissenschaften und Mathematik / Biowissenschaften, Biologie, Biochemie
open_access (DINI-Set):open_access
Licence (English):License LogoCreative Commons - CC BY 4.0 - Attribution 4.0 International