Recovery-stress response of blood-based biomarkers
- The purpose of this study was to investigate blood-based biomarkers and their regulation with regard to different recovery-stress states. A total of 35 male elite athletes (13 badminton, 22 soccer players) were recruited, and two venous blood samples were taken: one in a ‘recovered’ state (REC) after a minimum of one-day rest from exercise and another one in a ‘non-recovered’ state (NOR) after a habitual loading microcycle. Overall, 23 blood-based biomarkers of different physiologic domains, which address inflammation, muscle damage, and tissue repair, were analyzed by Luminex assays. Across all athletes, only creatine kinase (CK), interleukin (IL-) 6, and IL-17A showed higher concentrations at NOR compared to REC time points. In badminton players, higher levels of CK and IL-17A at NOR were found. In contrast, a higher value for S100 calcium-binding protein A8 (S100A8) at REC was found in badminton players. Similar differences were found for BDNF in soccer players. Soccer players also showed increased levels of CK, and IL-6 at NOR compared to REC state. Several molecular markers were shown to be responsive to differing recovery-stress states, but their suitability as biomarkers in training must be further validated.
Author: | Sebastian HackerORCiDGND, Thomas ReichelGND, Anne HeckstedenGND, Christopher WeyhORCiDGND, Kristina GebhardtGND, Mark PfeifferORCiDGND, Alexander FerrautiORCiDGND, Michael KellmannORCiDGND, Tim Friedrich MeyerORCiDGND, Karsten KrügerGND |
---|---|
URN: | urn:nbn:de:hbz:294-86474 |
DOI: | https://doi.org/10.3390/ijerph18115776 |
Parent Title (English): | International journal of environmental Research and public health |
Publisher: | MDPI |
Place of publication: | Basel |
Document Type: | Article |
Language: | English |
Date of Publication (online): | 2022/02/23 |
Date of first Publication: | 2021/05/27 |
Publishing Institution: | Ruhr-Universität Bochum, Universitätsbibliothek |
Tag: | Monitoring badminton; chemokines; cytokines; muscle damage; soccer |
Volume: | 18 |
Issue: | 11 |
First Page: | 5776-1 |
Last Page: | 5776-12 |
Institutes/Facilities: | Lehr- und Forschungsbereich Trainingswissenschaft |
Dewey Decimal Classification: | Künste und Unterhaltung / Sport |
faculties: | Fakultät für Sportwissenschaft |
Licence (English): | Creative Commons - CC BY 4.0 - Attribution 4.0 International |